May 27th, 2014, 13:30 - 16:30
Sohngaardsholmsvej 49, room 49, 9000 Aalborg.
"Characterization of the ecophysiology of micropollutant degrading bacteria by quantitative mass spectrometry-based proteomics"
The objective of this PhD was devoted to pure-culture studies of the physiology of bacterial strains capable of degrading selected micropollutants. Using different strategies of quantitative MS-based proteomics the catabolism and influence of four different aromatic micropollutants (ibuprofen, triclosan, p-cresol, and gemfibrozil) were investigated.
The combined scientific work of this PhD project demonstrated that proteomics is a valuable technique for characterizing the catabolism of micropollutants and provided novel insight into the catabolism and bacterial resistance against micropollutants ibuprofen, triclosan, p-cresol, and gemfibrozil. Several of the catabolism/resistance-related proteins identified in this study should be further characterized; however, they represent potential candidates that can be used as enzyme markers for biodegradation.
- Associate Professor, Jeppe Lund Nielsen, Department of Biotechnology, Chemistry and Environmental Engineering, Aalborg University
- Associate Professor, Michael Toft Overgaard (chairman), Department of Biotechnology, Chemistry and Environmental Engineering
- Dr. Dirk Benndorf, Otto von Guericke University (OvGU), Institute of Process Engineering
- Professor, Carsten Suhr Jacobsen, De Nationale Geologiske Undersøgelser for Danmark og Grønland (GEUS)