Molecularly imprinted polymers are dense and rigid crosslinked products formed from crosslinker and a pre-polymerization complex between a functional monomer and a template molecule. Subsequently, the template molecule is removed, revealing well-defined binding sites in which the arrangement of functional groups is particularly suited for binding the template molecules or to a minor extent structurally related molecules. This results in effects of molecular recognition affected by the given imprinted molecule, i.e., the template.
Our project will be focused on engineering cheap and durable imprinted organic/inorganic hybrid materials in aqueous systems. Model compounds in range of sugars, oligosaccharides, and peptides will be chosen as target templates to be imprinted in order to build up the binding assays and evaluate the imprinting:
- Syntheses of functional monomers
- Covalently imprinted organic polymers and covalent rebinding
- Covalently imprinted hybrid materials and covalent rebinding
- Selectivity studies
- Surface imprinting